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potent nmda receptor antagonist (cpp)  (Swant)

 
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    Swant potent nmda receptor antagonist (cpp)
    Effects of ICV injection of (A) saline or different doses of AP5 <t>(NMDA</t> receptor antagonist) (B) 1 mM (C) 5 mM, and (D) 25 mM/5 μL saline into the lateral ventricle on the maintenance and reinstatement of morphine in conditioned place preference paradigm. Animals received saline or AP5 during the extinction period (free morphine period). In the reinstatement day, animals received only priming dose of morphine (1 mg/kg; SC). Data are presented as mean±SEM for 6–7 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. † P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day. +P<0.05, ++ P<0.01, and +++ P<0.001 different from the reinstatement day.
    Potent Nmda Receptor Antagonist (Cpp), supplied by Swant, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/potent nmda receptor antagonist (cpp)/product/Swant
    Average 90 stars, based on 1 article reviews
    potent nmda receptor antagonist (cpp) - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Reduction of the Morphine Maintenance by Blockade of the NMDA Receptors during Extinction Period in Conditioned Place Preference Paradigm of Rats"

    Article Title: Reduction of the Morphine Maintenance by Blockade of the NMDA Receptors during Extinction Period in Conditioned Place Preference Paradigm of Rats

    Journal: Basic and Clinical Neuroscience

    doi: 10.15412/J.BCN.03070407

    Effects of ICV injection of (A) saline or different doses of AP5 (NMDA receptor antagonist) (B) 1 mM (C) 5 mM, and (D) 25 mM/5 μL saline into the lateral ventricle on the maintenance and reinstatement of morphine in conditioned place preference paradigm. Animals received saline or AP5 during the extinction period (free morphine period). In the reinstatement day, animals received only priming dose of morphine (1 mg/kg; SC). Data are presented as mean±SEM for 6–7 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. † P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day. +P<0.05, ++ P<0.01, and +++ P<0.001 different from the reinstatement day.
    Figure Legend Snippet: Effects of ICV injection of (A) saline or different doses of AP5 (NMDA receptor antagonist) (B) 1 mM (C) 5 mM, and (D) 25 mM/5 μL saline into the lateral ventricle on the maintenance and reinstatement of morphine in conditioned place preference paradigm. Animals received saline or AP5 during the extinction period (free morphine period). In the reinstatement day, animals received only priming dose of morphine (1 mg/kg; SC). Data are presented as mean±SEM for 6–7 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. † P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day. +P<0.05, ++ P<0.01, and +++ P<0.001 different from the reinstatement day.

    Techniques Used: Injection, Saline, Conditioned Place Preference

    Effects of single dose injection of NMDA receptor antagonist (before extinction period) on the maintenance and reinstatement of morphine rewarding properties in conditioned place preference paradigm. Animals received a single injection of AP5(25 mM/5 μL saline; ICV) just after postconditioning CPP test. In this set of experiment, animals did not receive any drug (AP5) or saline/morphine during the extinction or reinstatement days. Data are presented as mean±SEM for 8 rats. **P<0.01 and *** P<0.001 different from the pretest day. †P<0.05 and ††† P<0.001 different from the posttest day. +P<0.05 and +++ P<0.001 different from the reinstatement day.
    Figure Legend Snippet: Effects of single dose injection of NMDA receptor antagonist (before extinction period) on the maintenance and reinstatement of morphine rewarding properties in conditioned place preference paradigm. Animals received a single injection of AP5(25 mM/5 μL saline; ICV) just after postconditioning CPP test. In this set of experiment, animals did not receive any drug (AP5) or saline/morphine during the extinction or reinstatement days. Data are presented as mean±SEM for 8 rats. **P<0.01 and *** P<0.001 different from the pretest day. †P<0.05 and ††† P<0.001 different from the posttest day. +P<0.05 and +++ P<0.001 different from the reinstatement day.

    Techniques Used: Injection, Conditioned Place Preference, Saline

    Effects of single dose injection of NMDA receptor antagonist on the reinstatement of morphine in conditioned place preference paradigm. Animals received a single injection of AP5(5 mM/5 μl saline; ICV) just prior to administration of priming dose of morphine (1 mg/kg; SC) in reinstatement day. Data are presented as mean±SEM for 8 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. †P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day.
    Figure Legend Snippet: Effects of single dose injection of NMDA receptor antagonist on the reinstatement of morphine in conditioned place preference paradigm. Animals received a single injection of AP5(5 mM/5 μl saline; ICV) just prior to administration of priming dose of morphine (1 mg/kg; SC) in reinstatement day. Data are presented as mean±SEM for 8 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. †P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day.

    Techniques Used: Injection, Conditioned Place Preference, Saline



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    potent nmda receptor antagonist (cpp)  (Swant)
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    Swant potent nmda receptor antagonist (cpp)
    Effects of ICV injection of (A) saline or different doses of AP5 <t>(NMDA</t> receptor antagonist) (B) 1 mM (C) 5 mM, and (D) 25 mM/5 μL saline into the lateral ventricle on the maintenance and reinstatement of morphine in conditioned place preference paradigm. Animals received saline or AP5 during the extinction period (free morphine period). In the reinstatement day, animals received only priming dose of morphine (1 mg/kg; SC). Data are presented as mean±SEM for 6–7 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. † P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day. +P<0.05, ++ P<0.01, and +++ P<0.001 different from the reinstatement day.
    Potent Nmda Receptor Antagonist (Cpp), supplied by Swant, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/potent nmda receptor antagonist (cpp)/product/Swant
    Average 90 stars, based on 1 article reviews
    potent nmda receptor antagonist (cpp) - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Effects of ICV injection of (A) saline or different doses of AP5 (NMDA receptor antagonist) (B) 1 mM (C) 5 mM, and (D) 25 mM/5 μL saline into the lateral ventricle on the maintenance and reinstatement of morphine in conditioned place preference paradigm. Animals received saline or AP5 during the extinction period (free morphine period). In the reinstatement day, animals received only priming dose of morphine (1 mg/kg; SC). Data are presented as mean±SEM for 6–7 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. † P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day. +P<0.05, ++ P<0.01, and +++ P<0.001 different from the reinstatement day.

    Journal: Basic and Clinical Neuroscience

    Article Title: Reduction of the Morphine Maintenance by Blockade of the NMDA Receptors during Extinction Period in Conditioned Place Preference Paradigm of Rats

    doi: 10.15412/J.BCN.03070407

    Figure Lengend Snippet: Effects of ICV injection of (A) saline or different doses of AP5 (NMDA receptor antagonist) (B) 1 mM (C) 5 mM, and (D) 25 mM/5 μL saline into the lateral ventricle on the maintenance and reinstatement of morphine in conditioned place preference paradigm. Animals received saline or AP5 during the extinction period (free morphine period). In the reinstatement day, animals received only priming dose of morphine (1 mg/kg; SC). Data are presented as mean±SEM for 6–7 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. † P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day. +P<0.05, ++ P<0.01, and +++ P<0.001 different from the reinstatement day.

    Article Snippet: Additionally, systemic injection of the potent NMDA receptor antagonist (CPP) with low dose does not impair extinction memory in a self-administration paradigm ( Kelamangalath, Swant, Stramiello, & Wagner, 2007 ).

    Techniques: Injection, Saline, Conditioned Place Preference

    Effects of single dose injection of NMDA receptor antagonist (before extinction period) on the maintenance and reinstatement of morphine rewarding properties in conditioned place preference paradigm. Animals received a single injection of AP5(25 mM/5 μL saline; ICV) just after postconditioning CPP test. In this set of experiment, animals did not receive any drug (AP5) or saline/morphine during the extinction or reinstatement days. Data are presented as mean±SEM for 8 rats. **P<0.01 and *** P<0.001 different from the pretest day. †P<0.05 and ††† P<0.001 different from the posttest day. +P<0.05 and +++ P<0.001 different from the reinstatement day.

    Journal: Basic and Clinical Neuroscience

    Article Title: Reduction of the Morphine Maintenance by Blockade of the NMDA Receptors during Extinction Period in Conditioned Place Preference Paradigm of Rats

    doi: 10.15412/J.BCN.03070407

    Figure Lengend Snippet: Effects of single dose injection of NMDA receptor antagonist (before extinction period) on the maintenance and reinstatement of morphine rewarding properties in conditioned place preference paradigm. Animals received a single injection of AP5(25 mM/5 μL saline; ICV) just after postconditioning CPP test. In this set of experiment, animals did not receive any drug (AP5) or saline/morphine during the extinction or reinstatement days. Data are presented as mean±SEM for 8 rats. **P<0.01 and *** P<0.001 different from the pretest day. †P<0.05 and ††† P<0.001 different from the posttest day. +P<0.05 and +++ P<0.001 different from the reinstatement day.

    Article Snippet: Additionally, systemic injection of the potent NMDA receptor antagonist (CPP) with low dose does not impair extinction memory in a self-administration paradigm ( Kelamangalath, Swant, Stramiello, & Wagner, 2007 ).

    Techniques: Injection, Conditioned Place Preference, Saline

    Effects of single dose injection of NMDA receptor antagonist on the reinstatement of morphine in conditioned place preference paradigm. Animals received a single injection of AP5(5 mM/5 μl saline; ICV) just prior to administration of priming dose of morphine (1 mg/kg; SC) in reinstatement day. Data are presented as mean±SEM for 8 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. †P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day.

    Journal: Basic and Clinical Neuroscience

    Article Title: Reduction of the Morphine Maintenance by Blockade of the NMDA Receptors during Extinction Period in Conditioned Place Preference Paradigm of Rats

    doi: 10.15412/J.BCN.03070407

    Figure Lengend Snippet: Effects of single dose injection of NMDA receptor antagonist on the reinstatement of morphine in conditioned place preference paradigm. Animals received a single injection of AP5(5 mM/5 μl saline; ICV) just prior to administration of priming dose of morphine (1 mg/kg; SC) in reinstatement day. Data are presented as mean±SEM for 8 rats. *P<0.05, ** P<0.01, and *** P<0.001 different from the pretest day. †P<0.05, †† P<0.01, and ††† P<0.001 different from the posttest day.

    Article Snippet: Additionally, systemic injection of the potent NMDA receptor antagonist (CPP) with low dose does not impair extinction memory in a self-administration paradigm ( Kelamangalath, Swant, Stramiello, & Wagner, 2007 ).

    Techniques: Injection, Conditioned Place Preference, Saline